Prostate Biopsy

It is essential to find the cause of an elevated PSA level before performing a prostate biopsy!


The conventional approach to prostate care has been to perform a biopsy in patients whose elevated PSA levels suggest the presence of prostate cancer. This is because tissue samples are required to either confirm or weaken the suspicion of cancer. The problem with this conventional approach is that the task of locating a suspicious area of tissue in the prostate using ultrasound is a little like looking for a needle in a haystack. This explains why 10 to 12 tissue samples are removed in a typical biopsy procedure.

This situation is unfortunate for many men because they are expected to endure, and suffer the possible consequences of, multiple jabs to the prostate gland. Added to this is the uncertainty of the desired negative result. It may be no more than a false negative. Indeed, in contrast to magnetic resonance imaging (MRI), ultrasound – the imaging technique used to guide conventional needle biopsy – usually does not allow your doctor to accurately distinguish between areas of healthy and suspicious tissue.


Elevated PSA Levels


While an elevated PSA level and symptoms such as the need to urinate frequently may be reasons to suspect prostate cancer, they may also be caused by prostatitis or a common condition known as benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate gland. Given the different possible scenarios, it is important to determine the cause of an elevated PSA level or other symptoms as soon as possible so that the right treatment can be administered. Significant PSA level changes are almost always linked to a detectable cause.

Many doctors recommend that their patients with elevated PSA levels undergo a procedure known as core needle biopsy because the cause of the elevated level may be related to prostate cancer. This recommendation is often given without first attempting to determine whether the patients in question have any suspicious areas of tissue in their prostate glands that would warrant a biopsy procedure. This is a suboptimal approach because MRI does enable such a determination. At the ALTA Klinik, we first use MRI to determine whether there are any suspicious areas of tissue in the prostate before recommending that our patients undergo an MRI-guided biopsy procedure involving the removal of a tissue sample directly from the suspicious area of tissue.

MRI of the Prostate

At our medical center, we use MRI to determine the cause of abnormal PSA levels. This imaging procedure enables us to identify suspicious areas of tissue that might be causing the elevated levels and that therefore warrant a biopsy procedure. The subsequent MRI-guided biopsy procedure enables us to remove tissue samples precisely from the areas of tissue in question, even if these areas are very small.

(-> More information about MRI of the Prostate)


Precision Prostate Biopsy with MRI

Precision prostate biopsy using MRI is far superior to the hit-or-miss ultrasound procedure.


Recent advances in the area of MRI-based diagnostic techniques provided a basis for the development of our MRI-guided, precision biopsy procedure. The use of MRI allows us to take tissue samples directly from suspicious masses of tissue in the prostate gland. The exact location and extent of such suspicious masses of tissue is identified in the context of the MRI examination prior to the biopsy. This means that we do not need to take multiple samples from different locations in the prostate gland, hoping to hit the right location. Instead, we go straight for the exact location of the suspicious tissue. Biopsies are necessary in cases of suspected prostate cancer because nothing short of a direct analysis of the tissue in question can confirm the presence of cancer and allow your doctor to evaluate the degree of risk associated with it.

In the biopsy procedure we use, access to the prostate is gained through the perineum and not through the wall of the rectum. This makes the prophylactic administration of antibiotics unnecessary. MRI is used to guide the procedure so as to ensure that a tissue sample is removed precisely from the site in question.

This precise, one-time biopsy provides the basis for a final diagnosis. Armed with this vital information, you and your doctor can discuss the available treatment options and implement the right treatment as soon as possible.

It is always important for us to work together with your doctor. However, if you have not been referred to us by a doctor, we will confer with you about the various treatment options and refer you to an appropriate medical center.


MRI scan showing suspicious mass of tissue in the prostate gland

Advantages of the Biopsy Procedure

What follows is a summary of the advantages of MRI-guided biopsy at the ALTA Klinik:

  • A biopsy is not carried out unless a suspicious area of tissue in the prostate has been detected and precisely localized.
  • The MRI-guided biopsy procedure enables your doctor to remove a sample of tissue directly from the suspicious area of tissue.
  • The procedure is carried out on an outpatient basis with the use of a local anesthetic.
  • Given that the access route to the prostate is through the perineum and not through the wall of the rectum, there is no need for the prophylactic administration of antibiotics.








Partnerklinik der Charite
Pathologie Partner


Alfred-Bozi-Str. 3
33602 Bielefeld
Tel: +49 521 260 555 44
Fax: +49 521 260 555 14

Reinhardtstr. 23-27
10117 Berlin
Tel: +49 30 814 501 8118
Fax: +49 30 814 501 8119

Mo-Do. 8 - 19 Uhr
Fr. 8 - 14 Uhr


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ALTA Klinik
Neuenkirchener Straße 97
33332 Gütersloh

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